NEURO-ONCOLOGY IN DEVELOPING COUNTRIES

Imaging in neuro-oncology

Imaging plays several key roles in managing brain tumors, including diagnosis, prognosis, and treatment response assessment. Ongoing challenges remain as new therapies emerge and there are urgent needs to find accurate and clinically feasible methods to noninvasively evaluate brain tumors before and after treatment. This review aims to provide an overview of several advanced imaging modalities ...

Hotspots in Neuro-Oncology

Pediatric oncology in developing countries: challenges and solutions.

n developed countries, pediatric cancers are one of the leading causes of death in children. As the under-5-year mortality rate in developing countries drops because of improved sanitation, immunization, and access to basic medical care, pediatric cancers become increasingly important, rising to a position of the third or fourth most common cause of childhood death. It is estimated that 80%-85%...

Essential medicines for pediatric oncology in developing countries.

The burden of cancer in children in low and middle income countries (LMICs) is substantial, comprising at least 80% of incident cases globally, and an even higher proportion of cancer-related deaths. With survival rates exceeding 80% in high income countries, it is imperative to transfer these successes to LMICs. A major challenge is the poor availability of safe, cost-effective chemotherapy. A...

Monoclonal antibodies in neuro-oncology

Monoclonal antibodies (mAbs) are used with increasing success against many tumors but, for brain tumors, the blood-brain barrier (BBB) is a special concern. The BBB prevents antibody entry to the normal brain; however, its role in brain tumor therapy is more complex. The BBB is closest to normal at micro-tumor sites; its properties and importance change as the tumor grows. In this review, evolv...